Dr. Jeff Ratliff talks with Dr. Ron Postuma about the clinical features associated with IGLON5 positivity, emphasizing the implications for practitioners in diagnosing and treating sleep and movement disorders.

A recent publication from a large RBD cohort in Spain examined postmortem brain tissue from individuals who had RBD. This study showed there was abnormal synuclein in the cells that control atonia (muscle paralysis) during REM sleep in all the participants.

A recent study led by NAPS investigators Drs. Erik St. Louis and Brad Boeve from Mayo Clinic validated the use of an in-home sleep recording device to detect REM sleep without atonia.

The RBD Severity Scale, also known as the "IRBD-SSS" (International REM Sleep Behavior Disorder Study Group Symptom Severity Scale), is a tool used to assess the severity of REM Sleep Behavior Disorder (RBD) symptoms by evaluating the frequency and intensity of dream content, vocalizations, body movements, and potential injuries experienced by the patient, often with input from their bed partner as well.New research sheds light on REM sleep behavior disorder and its link to neurodegenerative diseases like Parkinson's. 🧠🔬💤

New research sheds light on REM sleep behavior disorder and its link to neurodegenerative diseases like Parkinson's. 🧠🔬💤

Researchers found that higher levels of belly and arm fat are associated with increased risk of developing Alzheimer's and Parkinson's diseases, especially among those with lower muscle strength. The study showed that individuals with high belly fat had a 13% higher risk, and those with high arm fat had an 18% higher risk of these neurodegenerative diseases compared to their counterparts with lower fat levels.