CSF Markers of Neurodegeneration Alzheimer’s and Lewy Body Pathology in Isolated RBD (iRBD)

Written By Kaleidoscope Management Group
 
 
 

Researchers at Hospital Clinic of Barcelona, Spain analyzed cerebrospinal fluid (CSF) from 148 patients with isolated REM sleep behavior disorder (iRBD) to find biological signals linked to neurodegenerative diseases. The study team used advanced techniques to measure proteins, including misfolded alpha-synuclein and Alzheimer’s markers, and tracked participants longitudinally to determine whether these markers may predict disease development.

This study provides supportive evidence that misfolding in alpha synuclein is a strong predictor of who might develop Parkinson’s or dementia in the future.

 
Kaleidoscope Management Group
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