REM Sleep Behavior Disorder (RBD) is a disorder in which people talk or move during their dreaming sleep. People with RBD have higher risk of developing a neurological disorder, such as Parkinson’s disease, dementia with Lewy bodies or multiple system atrophy. This group of disorders – termed synucleinopathies – is our research focus. The main goal of NAPS is to develop neuroprotective treatments to delay or prevent synucleinopathies.

  • Do you act out your dreams? Are you living with RBD?

    Do you act out your dreams? Have you been diagnosed with REM Sleep Behavior Disorder? Explore resources and opportunities to participate in research.

    RBD Resources

  • Are you a scientist or industry partner?

    Learn more about REM Sleep Behavior Disorder and explore active areas of research and potential collaboration in synucleinopathies.

    Resources for Researchers

  • REMEDY | REM Sleep Behavior Disorder Education Delivery

    REMEDY is an educational portal offering information on RBD, clinical studies, research opportunities, and resources for patients, loved ones, physicians, and researchers.

    Explore Our Educational Portal
 

Join the RBD Registry

The NAPS Consortium on REM Sleep Behavior Disorder (RBD) has established a registry for individuals living with RBD, partners and family of someone diagnosed with RBD, and those wanting to learn more about RBD.

This information is used to identify study participants, assist care teams providing care to individuals with RBD and to study RBD treatments and outcomes.

 

Your privacy is important to us. All personal health information (PHI) is protected and stored in a HIPAA compliant system.

Recent RBD News

RBD in the News
IGLON5 Frequency in Idiopathic REM Sleep Behavior Disorder
IGLON5 Frequency in Idiopathic REM Sleep Behavior Disorder

Dr. Jeff Ratliff talks with Dr. Ron Postuma about the clinical features associated with IGLON5 positivity, emphasizing the implications for practitioners in diagnosing and treating sleep and movement disorders.

Read More →
Post-Mortem Neuropathology of Idiopathic RBD: A Case Series
Post-Mortem Neuropathology of Idiopathic RBD: A Case Series

A recent publication from a large RBD cohort in Spain examined postmortem brain tissue from individuals who had RBD. This study showed there was abnormal synuclein in the cells that control atonia (muscle paralysis) during REM sleep in all the participants.

Read More →
Validation of Automated Detection of REM Sleep without Atonia Using In-Laboratory and In-Home Recordings
Validation of Automated Detection of REM Sleep without Atonia Using In-Laboratory and In-Home Recordings

A recent study led by NAPS investigators Drs. Erik St. Louis and Brad Boeve from Mayo Clinic validated the use of an in-home sleep recording device to detect REM sleep without atonia.

Read More →
The RBD Severity Scale
The RBD Severity Scale

The RBD Severity Scale, also known as the "IRBD-SSS" (International REM Sleep Behavior Disorder Study Group Symptom Severity Scale), is a tool used to assess the severity of REM Sleep Behavior Disorder (RBD) symptoms by evaluating the frequency and intensity of dream content, vocalizations, body movements, and potential injuries experienced by the patient, often with input from their bed partner as well.New research sheds light on REM sleep behavior disorder and its link to neurodegenerative diseases like Parkinson's. 🧠🔬💤

Read More →
A Pontine-Medullary Loop Crucial for REM Sleep and its Deficit in Parkinson’s Disease
A Pontine-Medullary Loop Crucial for REM Sleep and its Deficit in Parkinson’s Disease

New research sheds light on REM sleep behavior disorder and its link to neurodegenerative diseases like Parkinson's. 🧠🔬💤

Read More →
Does Your Body Composition Affect Your Risk of Dementia or Parkinson's?
Does Your Body Composition Affect Your Risk of Dementia or Parkinson's?

Researchers found that higher levels of belly and arm fat are associated with increased risk of developing Alzheimer's and Parkinson's diseases, especially among those with lower muscle strength. The study showed that individuals with high belly fat had a 13% higher risk, and those with high arm fat had an 18% higher risk of these neurodegenerative diseases compared to their counterparts with lower fat levels.

Read More →